Future motherboards will support Itanium or Xeon. http://www.bit-tech.net/news/hardware/2012/11/09/intel-drops-itanium/1
The founding issue with Itanium is that its EPIC architecture philosophy is simply too far removed from the modern trends in the industry, like power efficiency, uniform top-down scalability (from mobile to server) and broad software compatibility. And the thing is just too expensive to build, since to be an efficient ISA it needs a ton of cache memory to keep the static scheduled wide pipeline fed with data and instructions.
And a ton of cache is what it does have. Since these are premium chips it doesn't matter that Intel has to spend more die area on cache - the customer pays for it anyway.
