I just bought a new motherboard, Asus Maximus II GENE iP45, for my project. I know it's Crossfire compatible, but if I don't link 2 GPUs in SLI and just leave them separate (in configuration: GTX 295 + GTS 250 for physx), that should work, right? Didn't buy GTX 295 yet and holding off from buying ATI cards, as I'm much into folding and as I'm aware ATi hasn't been yet optimised for folding@home. And in this set up I'll be able to fold on all GPUs too. What do you think? Will it work? Thanks.