My idea would typically consist of multiple pico-itx boards, but 1 is still doable. since pico-itx has a form factor smaller than 4", it would definitely fit in the 5.25" drive bays, possibly even the HDD bays. My idea was to take a full atx case with at least 4 (preferably more) 5.25" drive bays. The front of these bays should be a mesh material, just like this case. Zoom in to see the texture. All slots would consist of one the LP-170s. Behind each one I would mount fans that would suck in air. Each LP-170 would have it's ports facing out the front of the computer. If you don't want people having access to the LP-170s, just stick the mesh 5.25" cover over it. Then, I would put in any generic motherboard in the main tray of the tower, with several PCI or PCI-e 1x slots. Each slot would have an Ethernet adapter in it. This is so each of the LP-170s can connect as a cluster computer. The built-in Ethernet port in the motherboard would be the main Internet or LAN connection. Next I would put in at least 2 hard drives. One would be for the main motherboard, the other would be for the cluster of LP-170s, which would do a network boot. After, I would take each of the Molex and floppy power connectors, cut off the ends, and solder the proper end for the LP-170. Obviously I would add whatever components I need to make sure the voltage is correct. As the final touch, the main power button of the tower would be used to power the main motherboard, and I would solder the reset button to turn on all of the LP-170s at the same time. An external DVD drive would be needed to install the OSes. Basically, my idea is to create a low-power cluster server inside of a desktop computer. Of course, you could just get an 8-core Xeon which would probably be faster, but also tremendously more expensive.