If your printer is now printing blank labels it's probably a Windows update that's screwed it. Dymo suggest uninstalling and reverting to DYMO Label Software v.8.5.4 but unhelpfully don't provide an embedded link. I uninstalled the current version and installed 8.5.1 and my printer is now working again. Make sure you have all your address books backed up before starting. Edit: The link to 8.5.4 is on the Dymo Home Page
I was lucky. I'd done a Windows update earlier so was able to work out pretty quickly that it might be related. After saying that I had another LabelWriter 450 in my Amazon basket before I realised that might be the reason followed by a quick google to check. I use mine on a regular basis, especially since I found you can laminate the genuine labels. Generic labels go grey when you laminate them.
I uninstalled mine including the drivers before reinstalling. I also uninstalled something else Dymo related at the same time but can't remember what it was. I also disconnected and reconnected the power and USB leads. As mentioned above back up your address books as the uninstall might remove them depending on whether you installed at the default location. Just in case none of the above fix it the following is the uninstall instructions Dymo sent me a couple of years ago to help fix a problem: 1. Close Dymo Label Software 2. Disconnect the Dymo printer from the computer 3. Restart your computer with the printer disconnected 4. Go to Start > Control Panel > Programs & Features > and remove Dymo Label Software v8 5. Once the uninstall is completed you go and remove the installation folder: 32bit - C:\Program Files\DYMO (v.8.x.x) 64bit - C:\Program Files (x86)\DYMO (v.8.x.x) 5.1 Go to C:\ProgramData and remove the DYMO folder 5.2 Go to C:\Users\-Your-User Name-\Documents and remove the DYMO Label folder 6. Go to this hidden folder - C:\Users\-Your-User Name-\App Data\Local\ , and remove DYMO and Sandford,_L.P folders 7. Reboot the computer once more, to make sure that the changes have been made. Still keep the printer disconnected. 8. Once the computer has restarted, download and install the latest version of the software 9. Once the installation is completed, then connect the printer directly to the computer, do not use a USB hub or docking station, and make sure that Windows finds and installs the printer correctly. 10. Open up Control Panel > Device & Printers and see if the printer shows up as a Printer
Just pause updates until MS fix their **** . My 450 printed a blank today, I remember reading an article a few days ago so I dug it out and read it, typical MS breaking things.