Yes they are very tasty boards and were on my list at one point. I think the convenience of having everything onboard makes it a good value case. Back to OS wise, have you looked at unraid? I know 6.9 added support for AMD. You could have a cache pool of your SSD's and then rust spinners for the arrays. It was a good blend of ease and the ability to unleash it where needed later. Personally in the end it wasnt for me, but it is still an amazing bit of software.