I have two 240mm radiators which I was thinking of running in the following order: Pump/res > GPU > CPU > 240mm Coolstream SE > 240mm Coolstream XE > back to pump/res. Any issues/thoughts on running them in line like this? Trying to workout a nice clean layout for a loop in a Meshify C and this order make it a bit easier to run the pipes, as the block on the GPU exits out of the rear rather than the side.
That will be fine, the order of the loop doesn't matter and having thembin that order won't affect the temps at all.
As Crapman said - order of the loop doesn’t really matter. So doing it the least restrictive/best looking way is the best way to plumb it. Only order that does matter is res -> pump